Objective: In our study, we aimed to compare the body mass index in the full-blown phenotype, which is a phenotype that includes all of the diagnostic criteria of polycystic ovary syndrome (PCOS) and non-androgenic Polycystic ovary syndrome.
Design: Prospective observational study
Setting: Gynecology and obstetrics clinic in tertiary hospital
Materials and methods: Sample population was divided into two phenotypes based on the NIH (National Institute of Health) consensus panel criteria. The Full-blown PCOS phenotype is the phenotype that includes all of the diagnostic criteria. The non-androgenic PCOS phenotype is named phenotype D. After the patients were divided into two groups, the body mass index of the patients was measured and compared statistically.
Results: Although there were 34 patients (55%) in the PCOS Phenotype A patient group, 28 (45%) patients in the PCOS phenotype D group and the study population consisted of 62 patients. Mean BMI of phenotype A patient group was 26.7±3.9 and mean BMI of phenotype d patient group was 23,2±4,1. When the BMI of both PCOS groups was compared statistically, Phenotype A group had significantly higher BMI than Phenotype D.
Conclusion: Full-blown PCOS (phenotype A) has a higher BMI compared to Phenotype D and higher risk for metabolic and cardiovascular risk in the literature than other PCOS phenotypes. Non-androgenic phenotype D has reduced risk then phenotype A PCOS in terms of metabolic and caridiovascular risk due to its normal androgenic level.
Anahtar Kelimeler: İnfertility, Metabolic syndrome, Obesity, Polycystic ovary syndrome
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